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| Second Basemen Single-Season RBIs Leaderboard | |
| * - Indicates Hall of Fame |
| Rank | Player | RBIs | PA | Year | Career Leaderboard |
| 1. | Gary Crawford | 118 | 686 | 2001 | |
| 2. | Bob Medforth | 116 | 671 | 2026 | |
| 3. | Summer Nelson * | 115 | 615 | 2015 | |
| Summer Nelson * | 115 | 651 | 2006 | ||
| 5. | Summer Nelson * | 109 | 657 | 2007 | |
| Gary Crawford | 109 | 593 | 2004 | ||
| 7. | Seamus O'Dule * | 108 | 657 | 2014 | |
| 8. | Bob Medforth | 107 | 656 | 2021 | |
| Summer Nelson * | 107 | 665 | 2013 | ||
| Rey Moncayo * | 107 | 644 | 2009 | ||
| 11. | Looney Garmendia | 106 | 680 | 2029 | |
| Dan Erb | 106 | 641 | 2018 | ||
| Ernest Meleschi | 106 | 626 | 2015 | ||
| 14. | Jack Hesse | 105 | 704 | 2029 | |
| Joseph Flores | 105 | 614 | 2025 | ||
| Daniel Phillips | 105 | 628 | 2024 | ||
| Bob Medforth | 105 | 671 | 2022 | ||
| 18. | Summer Nelson * | 103 | 680 | 2014 | |
| 19. | Henry Davis | 102 | 579 | 2018 | |
| Summer Nelson * | 102 | 672 | 2012 | ||
| 21. | Bob Medforth | 101 | 686 | 2019 | |
| Summer Nelson * | 101 | 661 | 2011 | ||
| Seamus O'Dule * | 101 | 660 | 2010 | ||
| William Maxon | 101 | 706 | 2001 | ||
| 25. | Rene Searles | 100 | 616 | 2017 | |
| Brian Marshall * | 100 | 629 | 2016 | ||
| William Maxon | 100 | 702 | 2000 | ||
| 28. | Andrew Wilson | 99 | 641 | 2028 | |
| Mark Stone | 99 | 634 | 2028 | ||
| Matthew Wolf | 99 | 596 | 2026 | ||
| Summer Nelson * | 99 | 641 | 2019 | ||
| Bobby Whittaker | 99 | 627 | 2018 | ||
| 33. | Looney Garmendia | 98 | 624 | 2028 | |
| Mark Stone | 98 | 651 | 2027 | ||
| Andrew Wilson | 98 | 661 | 2025 | ||
| Andrew Wilson | 98 | 605 | 2024 | ||
| Adam Anderson | 98 | 627 | 2010 | ||
| Rey Moncayo * | 98 | 678 | 2007 | ||
| Brian Marshall * | 98 | 662 | 2007 | ||
| 40. | Blinky Crouch | 97 | 600 | 2029 | |
| Ernest Meleschi | 97 | 593 | 2018 | ||
| Summer Nelson * | 97 | 679 | 2008 | ||
| Antonio Ramos | 97 | 710 | 2001 | ||
| 44. | Bob Medforth | 96 | 636 | 2023 | |
| Daniel Phillips | 96 | 635 | 2023 | ||
| Summer Nelson * | 96 | 646 | 2016 | ||
| Ludwig Claus | 96 | 607 | 2009 | ||
| 48. | Daniel Phillips | 95 | 598 | 2028 | |
| Joel Huertas | 95 | 643 | 2025 | ||
| Seamus O'Dule * | 95 | 661 | 2013 | ||
| 51. | Joel Huertas | 94 | 660 | 2026 | |
| Daniel Phillips | 94 | 662 | 2022 | ||
| Todd Maher | 94 | 567 | 2005 | ||
| 54. | Daniel Phillips | 93 | 671 | 2021 | |
| Randy McKen | 93 | 456 | 2019 | ||
| Rey Moncayo * | 93 | 695 | 2012 | ||
| Cyril Foland | 93 | 557 | 2010 | ||
| Summer Nelson * | 93 | 651 | 2005 | ||
| 59. | Andrew Wilson | 92 | 699 | 2027 | |
| Daniel Phillips | 92 | 662 | 2020 | ||
| Bob Medforth | 92 | 632 | 2018 | ||
| Brian Marshall * | 92 | 644 | 2012 | ||
| Howard Luther | 92 | 610 | 2008 | ||
| Lane Commons * | 92 | 628 | 2006 | ||
| 65. | Blinky Crouch | 91 | 650 | 2026 | |
| Daniel Phillips | 91 | 648 | 2019 | ||
| Allen Lively | 91 | 621 | 2016 | ||
| Henry Davis | 91 | 605 | 2016 | ||
| Allen Lively | 91 | 585 | 2015 | ||
| Rey Moncayo * | 91 | 673 | 2006 | ||
| Todd Maher | 91 | 730 | 2004 | ||
| Summer Nelson * | 91 | 718 | 2001 | ||
| 73. | Lane Commons * | 90 | 680 | 2016 | |
| Ludwig Claus | 90 | 627 | 2014 | ||
| Lane Commons * | 90 | 647 | 2009 | ||
| Howard Luther | 90 | 596 | 2009 | ||
| 77. | Jake Kinchen | 89 | 621 | 2021 | |
| David Melgoza | 89 | 642 | 2018 | ||
| Summer Nelson * | 89 | 615 | 2017 | ||
| Seamus O'Dule * | 89 | 662 | 2015 | ||
| Ernest Meleschi | 89 | 578 | 2012 | ||
| John Honeycutt | 89 | 504 | 2007 | ||
| Seamus O'Dule * | 89 | 620 | 2005 | ||
| Summer Nelson * | 89 | 672 | 2004 | ||
| 85. | Micheal Harrell | 88 | 652 | 2029 | |
| Mark Stone | 88 | 639 | 2026 | ||
| Bob Medforth | 88 | 654 | 2020 | ||
| Summer Nelson * | 88 | 668 | 2018 | ||
| Rey Moncayo * | 88 | 680 | 2011 | ||
| Brian Marshall * | 88 | 637 | 2009 | ||
| 91. | Daniel Phillips | 87 | 596 | 2025 | |
| Bob Medforth | 87 | 565 | 2025 | ||
| Daniel Phillips | 87 | 647 | 2015 | ||
| Brian Marshall * | 87 | 640 | 2013 | ||
| Ernest Meleschi | 87 | 619 | 2010 | ||
| Gary Crawford | 87 | 613 | 2005 | ||
| Antonio Ramos | 87 | 619 | 2002 | ||
| Brian Marshall * | 87 | 762 | 2000 | ||
| 99. | Mark Stone | 86 | 634 | 2029 | |
| Blinky Crouch | 86 | 598 | 2028 |
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