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| Second Basemen Career Salary Leaderboard | |
| * - Indicates Hall of Fame Bold - Indicates active player |
| Rank | Player | Salary | Years | Single Season Leaderboard | |
| 1. | Antonio Ramos | $42,780,000 | 2000-2008 | ||
| 2. | Gary Crawford | $25,140,000 | 2000-2009 | ||
| 3. | James Dickson | $20,340,000 | 2000-2009 | ||
| 4. | Joseph Sharkey | $20,112,000 | 2000-2005 | ||
| 5. | Zachary Matthews * | $18,840,000 | 2000-2012 | ||
| William Maxon | $18,840,000 | 2000-2008 | |||
| 7. | Darius Mosqueda | $18,540,000 | 2000-2011 | ||
| 8. | Joel Camacho | $17,940,000 | 2000-2005 | ||
| 9. | Larry Place | $14,640,000 | 2000-2006 | ||
| 10. | Jose Abdullah | $14,340,000 | 2000-2005 | ||
| David Strothers | $14,340,000 | 2000-2005 | |||
| 12. | Danny Rayborn | $12,900,000 | 2000-2008 | ||
| Todd Maher | $12,900,000 | 2000-2008 | |||
| 14. | Humberto Dominguez | $12,600,000 | 2000-2011 | ||
| 15. | John Lafever | $12,300,000 | 2000-2006 | ||
| Chas Cleek | $12,300,000 | 2000-2006 | |||
| Frederick Traynor | $12,300,000 | 2000-2006 | |||
| 18. | Blinky Crouch | $12,270,000 | 2018-2029 | ||
| 19. | Mark Stone | $12,210,000 | 2018-2029 | ||
| 20. | Anthony Godwin | $11,268,000 | 2015-2029 | ||
| 21. | Keith Johnson | $11,100,000 | 2000-2010 | ||
| 22. | Matthew Wolf | $10,810,000 | 2015-2029 | ||
| 23. | Alexander Bologna | $9,560,000 | 2000-2003 | ||
| 24. | Larry Banning | $9,528,000 | 2000-2008 | ||
| 25. | Jesus Tabares | $8,962,000 | 2022-2029 | ||
| 26. | Joseph Flores | $8,900,000 | 2019-2029 | ||
| 27. | Brett Eisen | $8,829,000 | 2000-2011 | ||
| 28. | Garry Vandiver | $8,710,000 | 2020-2029 | ||
| 29. | Matthew Dismukes | $8,628,000 | 2000-2005 | ||
| 30. | Looney Garmendia | $7,880,000 | 2027-2029 | ||
| 31. | Oscar Nolan | $7,810,000 | 2019-2029 | ||
| 32. | Joel Huertas | $7,340,000 | 2014-2029 | ||
| 33. | Freeman Delaune | $7,200,000 | 2000-2005 | ||
| 34. | Andrew Wilson | $6,810,000 | 2024-2029 | ||
| 35. | Jack Hesse | $6,800,000 | 2026-2029 | ||
| 36. | John Honeycutt | $6,442,500 | 2003-2013 | ||
| 37. | Dude Gallagher | $6,440,000 | 2019-2029 | ||
| 38. | Pedro Santillo | $6,400,000 | 2000-2004 | ||
| 39. | Jim Masson | $6,320,000 | 2016-2029 | ||
| 40. | Summer Nelson * | $6,300,000 | 2000-2020 | ||
| 41. | Snap Collins | $6,150,000 | 2022-2029 | ||
| 42. | Freddy Lozano | $6,000,000 | 2000-2005 | ||
| Gaston Jacobson | $6,000,000 | 2000-2005 | |||
| Hector Rodriguez | $6,000,000 | 2000-2002 | |||
| Seamus O'Dule * | $6,000,000 | 2002-2021 | |||
| 46. | William Kulas | $5,886,000 | 2000-2009 | ||
| 47. | Jake Kinchen | $5,720,000 | 2017-2029 | ||
| 48. | Brian Marshall * | $5,700,000 | 2000-2018 | ||
| 49. | Dave Dancey | $5,610,000 | 2020-2029 | ||
| 50. | Mason Highsmith | $5,400,000 | 2007-2024 | ||
| 51. | Dick Fink | $5,200,000 | 2000-2007 | ||
| 52. | Bobby Whittaker | $5,100,000 | 2010-2026 | ||
| Todd Castiglia | $5,100,000 | 2000-2016 | |||
| Vin Koenig | $5,100,000 | 2007-2023 | |||
| Ludwig Claus | $5,100,000 | 2005-2021 | |||
| 56. | Andy Pough | $4,810,000 | 2000-2004 | ||
| 57. | Kenneth Jarvis | $4,800,000 | 2000-2005 | ||
| Thomas Thomas | $4,800,000 | 2000-2003 | |||
| Samuel Warlick | $4,800,000 | 2001-2016 | |||
| James Erickson | $4,800,000 | 2005-2020 | |||
| Adam Anderson | $4,800,000 | 2001-2016 | |||
| 62. | William Mallory | $4,770,000 | 2000-2007 | ||
| 63. | Bates Schatz | $4,742,857 | 2024-2029 | ||
| 64. | Vince Rice | $4,656,000 | 2000-2002 | ||
| 65. | Jeff Arnette | $4,560,000 | 2021-2029 | ||
| 66. | Daniel Phillips | $4,500,000 | 2014-2028 | ||
| Rene Searles | $4,500,000 | 2011-2025 | |||
| Lane Commons * | $4,500,000 | 2003-2017 | |||
| Henry Davis | $4,500,000 | 2005-2020 | |||
| Tamajirou Kakuzo | $4,500,000 | 2015-2029 | |||
| 71. | Matt Lake | $4,216,000 | 2023-2029 | ||
| 72. | Henry Magnan | $4,200,000 | 2014-2027 | ||
| Bruce Howes | $4,200,000 | 2001-2014 | |||
| 74. | Luis Osalde | $4,180,000 | 2021-2029 | ||
| 75. | Kevin Barr | $4,037,500 | 2000-2011 | ||
| 76. | Fernando Selso | $4,028,571 | 2024-2029 | ||
| 77. | Josephus Thomas | $3,900,000 | 2004-2016 | ||
| Manuel Rodriguez | $3,900,000 | 2007-2019 | |||
| Abe Seemann | $3,900,000 | 2005-2017 | |||
| Dan Erb | $3,900,000 | 2009-2021 | |||
| Ernest Meleschi | $3,900,000 | 2007-2019 | |||
| David Melgoza | $3,900,000 | 2010-2023 | |||
| George Mingham | $3,900,000 | 2010-2023 | |||
| Rey Moncayo * | $3,900,000 | 2002-2014 | |||
| 85. | Darron Celestin | $3,885,000 | 2000-2004 | ||
| 86. | David Cimino | $3,600,000 | 2009-2020 | ||
| Harvey Thornton | $3,600,000 | 2016-2028 | |||
| Allen Lively | $3,600,000 | 2011-2022 | |||
| Albert Estrada | $3,600,000 | 2000-2012 | |||
| Howard Luther | $3,600,000 | 2003-2014 | |||
| Bob Hamada | $3,600,000 | 2017-2028 | |||
| 92. | Leon Nickles | $3,378,571 | 2025-2029 | ||
| 93. | John Hope | $3,352,000 | 2000-2003 | ||
| 94. | Tanner Valencia | $3,335,714 | 2027-2029 | ||
| 95. | Adrian Turgeon | $3,300,000 | 2017-2029 | ||
| David Reddaway | $3,300,000 | 2019-2029 | |||
| Cyril Foland | $3,300,000 | 2003-2013 | |||
| Howard Pierre | $3,300,000 | 2016-2027 | |||
| Bradford Erskine | $3,300,000 | 2014-2026 | |||
| Eugene Hove | $3,300,000 | 2007-2017 | |||
| Bob Alfred | $3,300,000 | 2012-2022 | |||
| Robert Souders | $3,300,000 | 2003-2013 | |||
| Brendan Conners | $3,300,000 | 2005-2015 | |||
| Joshua Sidwell | $3,300,000 | 2014-2024 | |||
| Bob Medforth | $3,300,000 | 2018-2029 | |||
| Randy McKen | $3,300,000 | 2012-2022 |
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