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| Career Winning Pct Leaderboard | |
| * - Indicates Hall of Fame Bold - Indicates active player |
| Rank | Player | Winning Pct | IP | Years | Single Season Leaderboard |
| 1. | J.L. Carrillo | .7472 | 1629.3 | 2018-2026 | |
| 2. | Kevin Smith | .7464 | 2599.0 | 2019-2029 | |
| 3. | Ralph Ives | .7336 | 2623.6 | 2018-2029 | |
| 4. | Armando Mesta | .7200 | 1366.7 | 2023-2029 | |
| 5. | Chad Schmidt | .7171 | 3346.6 | 2015-2029 | |
| 6. | Ryan Turner * | .7165 | 3744.9 | 2001-2021 | |
| 7. | Daniel Peart | .7100 | 940.6 | 2013-2018 | |
| 8. | Armando Quinonez * | .7056 | 1638.6 | 2000-2007 | |
| 9. | Aaron Bacon * | .7014 | 3356.0 | 2000-2012 | |
| 10. | Manuel Nieves | .7013 | 2186.3 | 2020-2029 | |
| 11. | Shiro Ogusuku | .7000 | 1014.7 | 2025-2029 | |
| 12. | Alfonso Font | .6985 | 1275.3 | 2015-2029 | |
| 13. | James Yim * | .6910 | 4445.9 | 2003-2021 | |
| 14. | Leo Cleland * | .6794 | 2815.6 | 2004-2017 | |
| 15. | Jacob Perl | .6792 | 2679.6 | 2016-2029 | |
| 16. | Chale Crespa | .6745 | 2354.0 | 2019-2029 | |
| 17. | Wilfredo Arroyo | .6739 | 1658.6 | 2023-2029 | |
| 18. | Richard San Juan | .6738 | 3143.3 | 2017-2029 | |
| 19. | David Bonneau | .6667 | 1427.3 | 2021-2029 | |
| 20. | Todd Neary | .6640 | 2286.6 | 2019-2029 | |
| 21. | Ramon Cordova | .6612 | 2756.6 | 2017-2029 | |
| 22. | Dennis Couch | .6594 | 1271.3 | 2022-2029 | |
| 23. | Art Toczek * | .6570 | 2240.3 | 2011-2023 | |
| 24. | Alfonso Arevalo | .6569 | 2110.6 | 2000-2011 | |
| 25. | Clarence McNatt * | .6480 | 2894.0 | 2003-2017 | |
| 26. | Ben Lamela | .6425 | 3342.6 | 2008-2025 | |
| 27. | Robert Garza * | .6412 | 2458.6 | 2004-2015 | |
| 28. | William Piccolo | .6406 | 1146.6 | 2000-2006 | |
| 29. | Edgardo Castillo * | .6402 | 3758.6 | 2001-2018 | |
| 30. | Bobby Peench | .6400 | 1216.6 | 2008-2023 | |
| 31. | David Echegaray | .6393 | 4812.6 | 2003-2026 | |
| 32. | Andrew Albury | .6387 | 2407.3 | 2001-2014 | |
| 33. | Dmitrij Mitskevich | .6385 | 1244.3 | 2002-2006 | |
| 34. | Dennis Wright * | .6361 | 3380.6 | 2001-2014 | |
| 35. | Wayne Sorely | .6322 | 1648.0 | 2021-2029 | |
| 36. | George Aybar | .6318 | 2359.3 | 2007-2019 | |
| 37. | Pedro Carrasquillo | .6286 | 1099.3 | 2020-2029 | |
| 38. | Danny Day | .6263 | 2527.6 | 2014-2026 | |
| 39. | Alfonso Manrique | .6259 | 1333.7 | 2023-2029 | |
| 40. | Roderigo Pequero | .6221 | 2668.6 | 2018-2029 | |
| 41. | Amadeo Villerreal | .6207 | 1712.0 | 2018-2026 | |
| 42. | Christopher Millar | .6196 | 2633.3 | 2014-2029 | |
| 43. | Leonard Lubbers | .6179 | 2356.6 | 2003-2013 | |
| 44. | James Alexander | .6159 | 2806.6 | 2011-2026 | |
| 45. | Powell Hoffman | .6147 | 2091.7 | 2020-2029 | |
| 46. | Paul Hall | .6146 | 2664.0 | 2018-2029 | |
| 47. | Benny Suarez | .6127 | 2730.9 | 2016-2029 | |
| 48. | Joseph Smartt | .6115 | 2503.3 | 2002-2014 | |
| 49. | Manny Coronas | .6111 | 1156.6 | 2014-2029 | |
| 50. | Rafael Souza | .6096 | 2287.6 | 2003-2022 | |
| 51. | Jonathan Alexander | .6076 | 2154.6 | 2019-2029 | |
| 52. | Stuart Whyte | .6052 | 2143.3 | 2011-2022 | |
| 53. | Pete Leighburn | .6044 | 1550.7 | 2023-2029 | |
| 54. | Ty Mercury | .6039 | 1499.0 | 2008-2016 | |
| 55. | Geoff Stagner | .6037 | 2609.0 | 2011-2025 | |
| 56. | Mohammad Kemmer | .6034 | 938.0 | 2003-2015 | |
| 57. | Higinio Delmonte | .6024 | 3025.3 | 2014-2029 | |
| 58. | Pedro Ceasar | .6015 | 1160.6 | 2000-2009 | |
| 59. | Luis Alou | .6013 | 1429.6 | 2014-2028 | |
| 60. | Ralph Motors | .6000 | 953.6 | 2009-2022 | |
| John Reza | .6000 | 1107.0 | 2003-2011 | ||
| 62. | Ken Timperley | .5984 | 1086.3 | 2018-2029 | |
| 63. | Dennis Morelock * | .5977 | 4013.6 | 2003-2017 | |
| 64. | Carmine Whittingham | .5943 | 2224.6 | 2014-2026 | |
| 65. | Lowell Stang * | .5899 | 2987.9 | 2007-2021 | |
| 66. | Charles Lewandowski | .5894 | 2454.3 | 2017-2029 | |
| 67. | Humberto Deleon | .5889 | 3174.9 | 2014-2029 | |
| 68. | Joseph Seybert | .5887 | 1290.0 | 2000-2005 | |
| 69. | Gyro Costa | .5865 | 1203.0 | 2024-2029 | |
| 70. | Roberto Villagomez | .5848 | 2099.3 | 2013-2024 | |
| 71. | J.J. Cobb | .5836 | 3210.6 | 2000-2014 | |
| 72. | Tony Paz | .5833 | 866.0 | 2000-2012 | |
| 73. | Armand Banuelos | .5823 | 3088.0 | 2000-2012 | |
| 74. | Danny Richards | .5818 | 959.3 | 2009-2019 | |
| 75. | Robert Mansell | .5817 | 1435.6 | 2012-2025 | |
| 76. | Harry Kirton | .5815 | 1684.3 | 2022-2029 | |
| 77. | John Demar | .5804 | 1057.0 | 2000-2006 | |
| 78. | David Scoggin | .5778 | 1654.6 | 2000-2011 | |
| 79. | Xalbador Laguna | .5776 | 2146.0 | 2019-2029 | |
| 80. | Benicio Andaverde | .5774 | 2653.3 | 2016-2029 | |
| 81. | Blaine Titsworth | .5758 | 1930.6 | 2000-2009 | |
| 82. | Kyle Nunn | .5755 | 2003.6 | 2006-2021 | |
| 83. | Blitz Codd | .5754 | 1576.0 | 2022-2029 | |
| 84. | Alfonzo Cortez | .5724 | 1398.0 | 2000-2006 | |
| 85. | Osvaldo Pedraza | .5710 | 3311.0 | 2003-2017 | |
| 86. | Samuel Grijalva | .5700 | 958.0 | 2000-2005 | |
| 87. | Willie Marshall | .5698 | 1673.3 | 2000-2008 | |
| 88. | Deangelo Ramos * | .5680 | 1166.3 | 2003-2020 | |
| 89. | Darius Wells | .5669 | 2622.6 | 2015-2029 | |
| Kelvin Palen | .5669 | 2641.3 | 2000-2010 | ||
| 91. | Al West | .5655 | 2725.6 | 2017-2029 | |
| 92. | Donald Granger * | .5649 | 1025.0 | 2003-2017 | |
| 93. | Christopher Laird | .5648 | 853.0 | 2000-2011 | |
| 94. | Fred Washington | .5633 | 2303.3 | 2005-2019 | |
| 95. | Chip Herold | .5632 | 1621.6 | 2021-2029 | |
| 96. | Tobias Escobar | .5611 | 2817.9 | 2006-2019 | |
| 97. | Hugo Holt * | .5605 | 1108.3 | 2006-2021 | |
| Mark Torrence | .5605 | 2896.3 | 2002-2015 | ||
| 99. | Adam Burton | .5593 | 2164.9 | 2009-2022 | |
| 100. | Larry Burkholder | .5591 | 1105.0 | 2011-2024 |
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