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| Career Slugging Pct Leaderboard | |
| * - Indicates Hall of Fame Bold - Indicates active player |
| Rank | Player | Slugging Pct | PA | Years | Single Season Leaderboard |
| 1. | Ron Guinan | .5762 | 6039 | 2019-2029 | |
| 2. | Anthony Beckford * | .5685 | 7657 | 2000-2013 | |
| 3. | Jimmie Davis * | .5542 | 3724 | 2000-2006 | |
| 4. | Jose Chavero | .5536 | 4633 | 2022-2029 | |
| 5. | Andy Ping | .5523 | 5678 | 2021-2029 | |
| 6. | Felton Olney | .5521 | 10112 | 2013-2029 | |
| 7. | Cliff Butter | .5521 | 6965 | 2017-2029 | |
| 8. | Sully Sullivan * | .5392 | 5234 | 2000-2009 | |
| 9. | Ethan Teller | .5332 | 6162 | 2020-2029 | |
| 10. | Toshinobu Kashiwagi | .5318 | 4836 | 2021-2029 | |
| 11. | Pete Kahle * | .5260 | 11872 | 2000-2019 | |
| 12. | Larry Sears | .5233 | 8969 | 2014-2029 | |
| 13. | Harold Petrillo * | .5095 | 8516 | 2003-2019 | |
| 14. | Grady McDonaghey * | .5077 | 8964 | 2006-2020 | |
| 15. | Tanner Chayse * | .5066 | 11089 | 2000-2017 | |
| 16. | Tony Romo | .5062 | 7909 | 2013-2026 | |
| 17. | Armando Mesa | .5057 | 6656 | 2000-2010 | |
| 18. | Bill Dickie | .5048 | 6394 | 2020-2029 | |
| 19. | Greg Holt | .5047 | 4916 | 2021-2029 | |
| 20. | Christopher Cortese | .5040 | 5951 | 2000-2010 | |
| 21. | Alex Garza * | .5026 | 6820 | 2000-2011 | |
| 22. | Tyson Bacon * | .4973 | 13464 | 2000-2022 | |
| 23. | Bill Newbold | .4969 | 6756 | 2019-2029 | |
| 24. | Hank Carruthers | .4967 | 5422 | 2020-2029 | |
| 25. | Frank Gillbard | .4940 | 6457 | 2018-2029 | |
| 26. | T.J. Freeland | .4937 | 6791 | 2017-2029 | |
| 27. | Sanford Powers | .4928 | 10625 | 2014-2029 | |
| 28. | Antonio Hernandez | .4926 | 4746 | 2000-2008 | |
| 29. | Bill Hawking | .4904 | 5737 | 2020-2029 | |
| 30. | Sylvester Suarez | .4904 | 7271 | 2014-2028 | |
| 31. | Santo Tedesco | .4902 | 6445 | 2019-2029 | |
| 32. | Dennis Thiele | .4870 | 4487 | 2000-2006 | |
| 33. | Osvaldo Ramos | .4869 | 4943 | 2000-2012 | |
| 34. | Summer Nelson * | .4867 | 13326 | 2000-2020 | |
| 35. | Fred Haigney | .4865 | 3866 | 2023-2029 | |
| 36. | Alex Cabezas | .4848 | 7774 | 2003-2016 | |
| 37. | Thomas Holtzclaw | .4813 | 5446 | 2000-2009 | |
| 38. | Bick Horizon | .4802 | 5642 | 2007-2018 | |
| 39. | Harry Andrews | .4795 | 4890 | 2022-2029 | |
| 40. | Adrian Gomez | .4795 | 6188 | 2000-2010 | |
| 41. | Issac Phillips | .4787 | 8097 | 2012-2029 | |
| 42. | Calvin Pulley | .4786 | 6367 | 2019-2029 | |
| 43. | Christopher Stormes * | .4785 | 10512 | 2006-2023 | |
| 44. | Lane Commons * | .4782 | 9290 | 2003-2017 | |
| 45. | Malachi Sain * | .4773 | 5575 | 2000-2010 | |
| 46. | Renaldo Loera | .4772 | 5922 | 2000-2009 | |
| 47. | Glen Mallory | .4772 | 3401 | 2024-2029 | |
| 48. | Jacinto Leon | .4772 | 5871 | 2000-2010 | |
| 49. | Seamus O'Dule * | .4772 | 12061 | 2000-2021 | |
| 50. | Flyswatter Pentecost | .4764 | 5196 | 2020-2029 | |
| 51. | Thomas Walker | .4758 | 3890 | 2007-2013 | |
| 52. | John Gleaves | .4758 | 10897 | 2009-2027 | |
| 53. | Gustavo Vizcaino | .4757 | 3031 | 2024-2029 | |
| 54. | Lee Desilva | .4746 | 5741 | 2020-2029 | |
| 55. | Juan Castillo | .4740 | 4154 | 2000-2007 | |
| 56. | Aragorn King * | .4712 | 8621 | 2003-2016 | |
| 57. | Kelvin Varga | .4701 | 5140 | 2000-2008 | |
| 58. | Grubby Thompson | .4699 | 3370 | 2023-2029 | |
| 59. | Skipper Cage | .4676 | 5097 | 2022-2029 | |
| 60. | Josh Kapaun | .4668 | 4800 | 2000-2007 | |
| 61. | Bobby Russell | .4665 | 6133 | 2018-2029 | |
| 62. | Blinky Crouch | .4657 | 6751 | 2018-2029 | |
| 63. | Adam Anderson | .4649 | 8316 | 2001-2016 | |
| 64. | Rey Moncayo * | .4645 | 7698 | 2002-2014 | |
| 65. | Ron Brenton | .4641 | 7397 | 2000-2011 | |
| 66. | Paul Sidgwick | .4635 | 6554 | 2019-2029 | |
| 67. | Bill Long | .4626 | 5251 | 2000-2008 | |
| 68. | Jerry Jorge | .4624 | 8167 | 2015-2029 | |
| 69. | Bobby Nuņo | .4622 | 6736 | 2011-2025 | |
| 70. | Gary Crawford | .4617 | 5657 | 2000-2009 | |
| 71. | Bill Rawcliffe | .4616 | 4511 | 2022-2029 | |
| 72. | Carlos Salazar | .4609 | 4080 | 2000-2009 | |
| 73. | Matt McQuade * | .4601 | 10532 | 2003-2020 | |
| 74. | Blair Glaspie | .4600 | 5234 | 2021-2029 | |
| 75. | Tom Galaxy | .4599 | 6355 | 2019-2029 | |
| 76. | Christopher Ferrante * | .4595 | 8645 | 2003-2018 | |
| 77. | Johnny Carmona | .4584 | 6157 | 2003-2015 | |
| 78. | Rico Torreiro | .4576 | 3998 | 2021-2029 | |
| 79. | Vernon Castanon | .4568 | 4510 | 2004-2014 | |
| 80. | Mark Delia * | .4566 | 11162 | 2000-2018 | |
| 81. | Clarence Dibenedetto | .4561 | 8128 | 2005-2017 | |
| 82. | Eric Fender | .4558 | 5189 | 2020-2029 | |
| 83. | Gandalf Greyheme * | .4551 | 11069 | 2003-2020 | |
| 84. | Jimmy Font | .4550 | 10261 | 2010-2027 | |
| 85. | Andrew Wilson | .4544 | 3737 | 2024-2029 | |
| 86. | Bob Medforth | .4536 | 6924 | 2018-2029 | |
| 87. | Bernardo Liriano | .4523 | 3512 | 2000-2007 | |
| 88. | Brian Marshall * | .4521 | 12282 | 2000-2018 | |
| 89. | Jeffrey Foxwell | .4521 | 7836 | 2014-2027 | |
| 90. | Alesso Rusticucci | .4514 | 6761 | 2004-2016 | |
| 91. | Rudy Lareau | .4514 | 7843 | 2010-2025 | |
| 92. | Jarvis Holeman | .4505 | 8003 | 2007-2020 | |
| 93. | Mack Outlaw | .4505 | 3183 | 2025-2029 | |
| 94. | Tracy Jordan | .4499 | 4230 | 2000-2007 | |
| 95. | Ramon Baez | .4496 | 5422 | 2000-2008 | |
| 96. | Paul Urguidz | .4492 | 4502 | 2019-2029 | |
| 97. | Chris Lott | .4490 | 8546 | 2005-2018 | |
| 98. | Victor Gullo | .4484 | 9423 | 2012-2027 | |
| 99. | Hal Rehm | .4469 | 10482 | 2005-2022 | |
| 100. | Bill Lalonde | .4468 | 5561 | 2000-2010 |
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